A protein biosensor that relies on bending of single DNA molecules.
A "bendy" protein sensor: A DNA-based sensor that uses folded DNA (through DNA kinks) and protein-induced bending to detect DNA-binding proteins is presented. Single-molecule sensing of a transcriptional activator (catabolite activator protein, CAP, which bends its DNA site by 80°) is demo...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2012
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