Microsatellite genotyping and genome-wide single nucleotide polymorphism-based indices of Plasmodium falciparum diversity within clinical infections

BACKGROUND:In regions where malaria is endemic, individuals are often infected with multiple distinct parasite genotypes, a situation that may impact on evolution of parasite virulence and drug resistance. Most approaches to studying genotypic diversity have involved analysis of a modest number of p...

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Main Authors: Murray, L, Mobegi, VA, Duffy, CW, Assefa, SA, Kwiatkowski, DP, Laman, E, Loua, KM, Conway, DJ
格式: Journal article
语言:English
出版: BioMed Central 2016