A novel zinc-binding fold in the helicase interaction domain of the Bacillus subtilis DnaI helicase loader.

The helicase loader protein DnaI (the Bacillus subtilis homologue of Escherichia coli DnaC) is required to load the hexameric helicase DnaC (the B. subtilis homologue of E. coli DnaB) onto DNA at the start of replication. While the C-terminal domain of DnaI belongs to the structurally well-character...

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Bibliographic Details
Main Authors: Loscha, K, Jaudzems, K, Ioannou, C, Su, X, Hill, F, Otting, G, Dixon, N, Liepinsh, E
Format: Journal article
Language:English
Published: 2009