TPC2 proteins mediate nicotinic acid adenine dinucleotide phosphate (NAADP)- and agonist-evoked contractions of smooth muscle.

TPC2 proteins mediate nicotinic acid adenine dinucleotide phosphate (NAADP)- and agonist-evoked contractions of smooth muscle.

Agonists such as those acting at muscarinic receptors are thought to induce contraction of smooth muscle primarily through inositol 1,4,5-trisphosphate production and release of Ca(2+) from sarcoplasmic reticulum. However, the additional Ca(2+)-mobilizing messengers cyclic adenosine diphosphate ribo...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Tugba Durlu-Kandilci, N, Ruas, M, Chuang, K, Brading, A, Parrington, J, Galione, A
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2010

Antzeko izenburuak

Calcium signalling by nicotinic acid adenine dinucleotide phosphate (NAADP).
nork: Yamasaki, M, et al.
Argitaratua: (2005)

Unique kinetics of nicotinic acid-adenine dinucleotide phosphate (NAADP) binding enhance the sensitivity of NAADP receptors for their ligand.
nork: Patel, S, et al.
Argitaratua: (2000)

Photoaffinity labeling of high affinity nicotinic acid adenine dinucleotide phosphate (NAADP)-binding proteins in sea urchin egg.
nork: Walseth, T, et al.
Argitaratua: (2012)

Calcium stimulates the synthesis of nicotinic acid adenine dinucleotide phosphate (NAADP) in sea urchin sperm
nork: Lewis, A, et al.
Argitaratua: (2005)

Two pore channels (TPC2s) and nicotinic acid adenine dinucleotide phosphate (NAADP) at lysosomal-sarcoplasmic reticular junctions contribute to acute and chronic β-adrenoceptor signaling in the heart
nork: Capel, R, et al.
Argitaratua: (2015)

The Role of Calcium and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) in Human Osteoclast Formation and Resorption.
nork: Cheng, X, et al.
Argitaratua: (2015)

Production and characterization of reduced NAADP (nicotinic acid-adenine dinucleotide phosphate).
nork: Billington, R, et al.
Argitaratua: (2004)

Characterization of Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Binding Proteins
nork: Zhu, D
Argitaratua: (2018)

Analogues of the nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist Ned-19 indicate two binding sites on the NAADP receptor.
nork: Rosen, D, et al.
Argitaratua: (2009)

Nicotinic acid adenine dinucleotide phosphate (NAADP) regulates autophagy in cultured astrocytes.
nork: Pereira, G, et al.
Argitaratua: (2011)

To be or not to be… Nicotinic acid adenine dinucleotide phosphate (NAADP): A new intracellular second messenger?
nork: EDUARDO NUNES CHINI
Argitaratua: (2004-01-01)

To be or not to be… Nicotinic acid adenine dinucleotide phosphate (NAADP): A new intracellular second messenger?
nork: EDUARDO NUNES CHINI
Argitaratua: (2004-01-01)

Solubilization of receptors for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate.
nork: Berridge, G, et al.
Argitaratua: (2002)

The influence of nicotinic acid adenine dinucleotide phosphate (NAADP) signalling and the significance of the organization of lysosomes in cardiac myocytes
nork: Aston, D
Argitaratua: (2017)

The functional roles of Ca2+ mobilizing pyridine nucleotides cADPR and NAADP in detrusor and taenia caceum
nork: Durlu-Kandilci, N, et al.
Argitaratua: (2007)

Chemical synthesis of the second messenger nicotinic acid adenine dinucleotide phosphate by total synthesis of nicotinamide adenine dinucleotide phosphate.
nork: Dowden, J, et al.
Argitaratua: (2004)

Deviant nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated Ca2+ signaling upon lysosome proliferation.
nork: Dickinson, G, et al.
Argitaratua: (2010)

Nicotinic acid adenine dinucleotide phosphate (NAADP) is a second messenger in muscarinic receptor-induced contraction of guinea pig trachea.
nork: Aley, P, et al.
Argitaratua: (2013)

Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)-Mediated Calcium Signaling Is Active in Memory CD4<sup>+</sup> T Cells
nork: Anish Chakraborty, et al.
Argitaratua: (2024-02-01)

Chemo-enzymatic synthesis and biological evaluation of photolabile nicotinic acid adenine dinuclotide phosphate (NAADP+).
nork: Parkesh, R, et al.
Argitaratua: (2007)

Spatial control of Ca2+ signaling by nicotinic acid adenine dinucleotide phosphate diffusion and gradients.
nork: Churchill, G, et al.
Argitaratua: (2000)

Degradation of the novel calcium mobilizing messenger, nicotinic acid adenine dinucleotide phosphate, is calcium-dependent.
nork: Berridge, G, et al.
Argitaratua: (2001)

Nicotinic acid adenine dinucleotide phosphate mediates Ca2+ signals and contraction in arterial smooth muscle via a two-pool mechanism.
nork: Boittin, F, et al.
Argitaratua: (2002)

Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cells.
nork: Ruas Da Silva, I, et al.
Argitaratua: (2015)

Refinement of a radioreceptor binding assay for nicotinic acid adenine dinucleotide phosphate.
nork: Lewis, A, et al.
Argitaratua: (2007)

The ecto-enzyme CD38 is a nicotinic acid adenine dinucleotide phosphate (NAADP) synthase that couples receptor activation to Ca2+ mobilization from lysosomes in pancreatic acinar cells.
nork: Cosker, F, et al.
Argitaratua: (2010)

Widespread distribution of binding sites for the novel Ca2+-mobilizing messenger, nicotinic acid adenine dinucleotide phosphate, in the brain.
nork: Patel, S, et al.
Argitaratua: (2000)

Ca2+ releasing process and nicotinic acid adenine dinucleotide phosphate
nork: S. Bychkova
Argitaratua: (2013-09-01)

NAADP receptors.
nork: Galione, A, et al.
Argitaratua: (2005)

NAADP and cADPR signalling in sea urchin eggs
nork: Galione, A, et al.
Argitaratua: (2005)

Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking.
nork: Ruas, M, et al.
Argitaratua: (2010)

Nicotinic acid adenine dinucleotide phosphate regulates skeletal muscle differentiation via action at two-pore channels.
nork: Aley, P, et al.
Argitaratua: (2010)

The calcium-mobilizing messenger nicotinic acid adenine dinucleotide phosphate participates in sperm activation by mediating the acrosome reaction.
nork: Vasudevan, SR, et al.
Argitaratua: (2010)

Prolonged inactivation of nicotinic acid adenine dinucleotide phosphate-induced Ca2+ release mediates a spatiotemporal Ca2+ memory.
nork: Churchill, G, et al.
Argitaratua: (2001)

Fertilization and nicotinic acid adenine dinucleotide phosphate induce pH changes in acidic Ca(2+) stores in sea urchin eggs.
nork: Morgan, A, et al.
Argitaratua: (2007)

Calcium release from the endoplasmic reticulum of higher plants elicited by the NADP metabolite nicotinic acid adenine dinucleotide phosphate.
nork: Navazio, L, et al.
Argitaratua: (2000)

Lysosome-sarcoplasmic reticulum junctions. A trigger zone for calcium signaling by nicotinic acid adenine dinucleotide phosphate and endothelin-1.
nork: Kinnear, N, et al.
Argitaratua: (2004)

A functional role for nicotinic acid adenine dinucleotide phosphate in oxytocin-mediated contraction of uterine smooth muscle from rat.
nork: Aley, P, et al.
Argitaratua: (2010)

TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+.
nork: Pitt, S, et al.
Argitaratua: (2010)

Metabolism of the novel Ca2+-mobilizing messenger nicotinic acid-adenine dinucleotide phosphate via a 2'-specific Ca2+-dependent phosphatase.
nork: Berridge, G, et al.
Argitaratua: (2002)