p38 MAP kinase mediates apoptosis through phosphorylation of BimEL at Ser-65.

The stress-activated c-Jun N-terminal protein kinase (JNK) and p38 mitogen-activated protein (MAP) kinase (p38) regulate apoptosis induced by several forms of cellular insults. Potential targets for these kinases include members of the Bcl-2 family proteins, which mediate apoptosis generated through...

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Bibliographic Details
Main Authors: Cai, B, Chang, S, Becker, E, Bonni, A, Xia, Z
Format: Journal article
Language:English
Published: 2006