Visualizing protein-DNA interactions in live bacterial cells using photoactivated single-molecule tracking.

Protein-DNA interactions are at the heart of many fundamental cellular processes. For example, DNA replication, transcription, repair, and chromosome organization are governed by DNA-binding proteins that recognize specific DNA structures or sequences. In vitro experiments have helped to generate de...

Full description

Bibliographic Details
Main Authors: Uphoff, S, Sherratt, D, Kapanidis, A
Format: Journal article
Language:English
Published: 2014