Visualizing protein-DNA interactions in live bacterial cells using photoactivated single-molecule tracking.

Protein-DNA interactions are at the heart of many fundamental cellular processes. For example, DNA replication, transcription, repair, and chromosome organization are governed by DNA-binding proteins that recognize specific DNA structures or sequences. In vitro experiments have helped to generate de...

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Détails bibliographiques
Auteurs principaux: Uphoff, S, Sherratt, D, Kapanidis, A
Format: Journal article
Langue:English
Publié: 2014