Modeling of an ion channel in its open conformation.

We have modeled the structure of KirBac1.1 in an open state using as a starting point the structure of KirBac1.1 in its closed conformation (Protein Data Bank 1P7B). To test the validity of the open-state model, molecular dynamics simulations in octane, a lipid bilayer mimetic, were carried out. Sim...

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Váldodahkkit: Domene, C, Doyle, D, Vénien-Bryan, C
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2005