Modeling of an ion channel in its open conformation.

We have modeled the structure of KirBac1.1 in an open state using as a starting point the structure of KirBac1.1 in its closed conformation (Protein Data Bank 1P7B). To test the validity of the open-state model, molecular dynamics simulations in octane, a lipid bilayer mimetic, were carried out. Sim...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Domene, C, Doyle, D, Vénien-Bryan, C
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2005