Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag.

HIV avoids elimination by cytotoxic T-lymphocytes (CTLs) through the evolution of escape mutations. Although there is mounting evidence that these escape pathways are broadly consistent among individuals with similar human leukocyte antigen (HLA) class I alleles, previous population-based studies ha...

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Bibliografiska uppgifter
Huvudupphovsmän: Carlson, J, Brumme, Z, Rousseau, C, Brumme, C, Matthews, P, Kadie, C, Mullins, J, Walker, B, Harrigan, P, Goulder, P, Heckerman, D
Materialtyp: Journal article
Språk:English
Publicerad: 2008