Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops
<p>Hypoxia is a common feature of solid tumors and is associated with poor patient prognosis, therapy resistance and metastasis. Radiobiological hypoxia (<0.1% O<sub>2</sub>) is one of the few physiologically relevant stresses that activates both the replication stress/DNA d...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Oxford University Press
2023
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