Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops

<p>Hypoxia is a common feature of solid tumors and is associated with poor patient prognosis, therapy resistance and metastasis. Radiobiological hypoxia (&lt;0.1% O<sub>2</sub>) is one of the few physiologically relevant stresses that activates both the replication stress/DNA d...

詳細記述

書誌詳細
主要な著者: Ma, TS, Worth, KR, Maher, C, Ng, N, Beghè, C, Gromak, N, Rose, AM, Hammond, EM
フォーマット: Journal article
言語:English
出版事項: Oxford University Press 2023