Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops
<p>Hypoxia is a common feature of solid tumors and is associated with poor patient prognosis, therapy resistance and metastasis. Radiobiological hypoxia (<0.1% O<sub>2</sub>) is one of the few physiologically relevant stresses that activates both the replication stress/DNA d...
主要な著者: | , , , , , , , |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
Oxford University Press
2023
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