Neonatal diabetes - The role of KCNJ11 (Kir6.2)
ATP-sensitive potassium (KATP) channels are inhibited by intracellular ATP and activated by MgADP. As a consequence, they couple the metabolic state of the cell to its electrical activity. In pancreatic β-cells KATP channels regulate glucose-dependent insulin secretion and are the target for sulphon...
| Autore principale: | |
|---|---|
| Natura: | Journal article |
| Lingua: | English |
| Pubblicazione: |
2007
|