Neonatal diabetes - The role of KCNJ11 (Kir6.2)
ATP-sensitive potassium (KATP) channels are inhibited by intracellular ATP and activated by MgADP. As a consequence, they couple the metabolic state of the cell to its electrical activity. In pancreatic β-cells KATP channels regulate glucose-dependent insulin secretion and are the target for sulphon...
1. Verfasser: | Tammaro, P |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2007
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