No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls.

OBJECTIVES: Osteoarthritis (OA) has a complex aetiology with a strong genetic component. Genome-wide association studies implicate several nuclear genes in the aetiology, but a major component of the heritability has yet to be defined at the molecular level. Initial studies implicate maternally inhe...

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Bibliographic Details
Main Authors: Hudson, G, Panoutsopoulou, K, Wilson, I, Southam, L, Rayner, N, Arden, N, Birrell, F, Carluke, I, Carr, A, Chapman, K, Deloukas, P, Doherty, M, McCaskie, A, Ollier, W, Ralston, S, Reed, MR, Spector, T, Valdes, A, Wallis, G, Wilkinson, J, Zeggini, E, Samuels, D, Loughlin, J, Chinnery, P
Format: Journal article
Language:English
Published: 2013