Serotonin transporter polymorphisms (SLC6A4 insertion/deletion and rs25531) do not affect the availability of 5-HTT to [11C] DASB binding in the living human brain.

Studies in vitro suggest that the expression of the serotonin transporter (5-HTT) is regulated by polymorphic variation in the promoter region of the 5-HTT gene (5-HTTLPR); however, results from human brain imaging studies examining the relation between 5-HTT genotype and 5-HTT radioligand binding i...

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Bibliographic Details
Main Authors: Murthy, N, Selvaraj, S, Cowen, P, Bhagwagar, Z, Riedel, W, Peers, P, Kennedy, J, Sahakian, B, Laruelle, M, Rabiner, E, Grasby, P
Format: Journal article
Language:English
Published: 2010