A mechanistic evolutionary model explains the time-dependent pattern of substitution rates in viruses

Estimating viral timescales is fundamental in understanding the evolutionary biology of viruses. Molecular clocks are widely used to reveal the recent evolutionary histories of viruses but may severely underestimate their longer-term origins because of the inverse correlation between inferred rates...

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Bibliographic Details
Main Authors: Ghafari, M, Simmonds, P, Pybus, OG, Katzourakis, A
Format: Journal article
Language:English
Published: Cell Press 2021