Iminosugars in combination with interferon and ribavirin permanently eradicate noncytopathic bovine viral diarrhea virus from persistently infected cells.

We evaluated interferon (IFN) and ribavirin (RBV) as dual therapy and as part of triple-combination therapies with the iminosugars N-butyl-deoxynojirimycin (NB-DNJ), N-nonyl-deoxynojirimycin, and N-7-oxanonyl-6-deoxymethyl-galactonojirimycin. The ability of these compounds to clear bovine viral diar...

Full description

Bibliographic Details
Main Authors: Woodhouse, S, Smith, C, Michelet, M, Branza-Nichita, N, Hussey, M, Dwek, R, Zitzmann, N
Format: Journal article
Language:English
Published: American Society for Microbiology 2008