Antigen presentation and the association of class-I molecules.

We have identified two mutant cell lines which are not able to present epitopes of influenza virus synthesized in the cytoplasm but can present the same epitope when exposed to it as a peptide in the extracellular medium. The cell lines also have a defect in class-I assembly, with reduced expression...

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Autors principals: Elliott, T, Cerundolo, V, Ohlen, C, Ljunggren, H, Karre, K, Townsend, A
Format: Journal article
Idioma:English
Publicat: 1991