Hyperpolarized 13c magnetic resonance spectroscopy identifies changes to myocardial metabolic fluxes in a rat model of doxorubicin-induced cardiotoxicity

Hyperpolarized 13c magnetic resonance spectroscopy identifies changes to myocardial metabolic fluxes in a rat model of doxorubicin-induced cardiotoxicity

Manylion Llyfryddiaeth
Prif Awduron:	Timm, KN, Miller, JJ, Ball, V, Henry, JA, Savic, D, Dodd, MS, Tyler, DJ
Fformat:	Conference item
Iaith:	English
Cyhoeddwyd:	BMJ 2018

Eitemau Tebyg

Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI.
gan: Timm, KN, et al.
Cyhoeddwyd: (2020)

The role of AMPK activation for cardioprotection in doxorubicin-induced cardiotoxicity
gan: Timm, KN, et al.
Cyhoeddwyd: (2020)

Assessing the optimal preparation strategy to minimize the variability of cardiac pyruvate dehydrogenase flux measurements with hyperpolarized MRS
gan: Timm, KN, et al.
Cyhoeddwyd: (2018)

Hyperpolarized ketone body metabolism in the rat heart
gan: Miller, J, et al.
Cyhoeddwyd: (2018)

L-Carnitine stimulates in vivo carbohydrate metabolism in the Type 1 diabetic heart as demonstrated by hyperpolarized MRI
gan: Savic, D, et al.
Cyhoeddwyd: (2021)

The effect of hyperpolarized tracer concentration on myocardial uptake and metabolism.
gan: Schroeder, M, et al.
Cyhoeddwyd: (2009)

Simultaneous in vivo assessment of cardiac and hepatic metabolism in the diabetic rat using hyperpolarized MRS
gan: Le Page, L, et al.
Cyhoeddwyd: (2016)

Probing hepatic metabolism of [2-13C]dihydroxyacetone in vivo with 1H-decoupled hyperpolarized 13C-MR
gan: Marco-Rius, I, et al.
Cyhoeddwyd: (2020)

Hyperpolarized butyrate: a metabolic probe of short chain fatty acid metabolism in the heart.
gan: Ball, DR, et al.
Cyhoeddwyd: (2014)

Multi-parametric MRI evaluation of doxorubicin-induced cardiotoxicity in a canine model
gan: Hu, C, et al.
Cyhoeddwyd: (2019)

Hyperpolarized magnetic resonance shows that the antiischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved postischemic function in the diabetic heart
gan: Savic, D, et al.
Cyhoeddwyd: (2021)

Proof-of-principle demonstration of direct metabolic imaging following myocardial infarction using hyperpolarized 13C CMR
gan: Apps, A, et al.
Cyhoeddwyd: (2021)

Investigating the functional and metabolic role of carnitine in the diabetic heart using hyperpolarized MRI
gan: Savic, D
Cyhoeddwyd: (2018)

An Engineered Bivalent Neuregulin Protects Against Doxorubicin-Induced Cardiotoxicity With Reduced Proneoplastic Potential
gan: Jay, Steven M., et al.
Cyhoeddwyd: (2014)

Assessing the effect of anesthetic gas mixtures on hyperpolarized 13C pyruvate metabolism in the rat brain
gan: Healicon, R, et al.
Cyhoeddwyd: (2022)

Mollification of doxorubicin (DOX)-mediated cardiotoxicity using conjugated chitosan nanoparticles with supplementation of propionic acid
gan: Siva, Durairaj, et al.
Cyhoeddwyd: (2022)

Linking diabetic cardiovascular disease with non-alcoholic fatty liver disease through L-carnitine: A hyperpolarized MRS study
gan: Savic, D, et al.
Cyhoeddwyd: (2019)

Rapid, B1-insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux
gan: Miller, JJ, et al.
Cyhoeddwyd: (2021)

Robust and high resolution hyperpolarized metabolic imaging of the rat heart at 7 t with 3d spectral-spatial EPI.
gan: Miller, J, et al.
Cyhoeddwyd: (2015)

Susceptibility‐induced distortion correction in hyperpolarized echo planar imaging
gan: Miller, JJ, et al.
Cyhoeddwyd: (2017)

Application of hyperpolarized magnetic resonance in the study of cardiac metabolism
gan: Tyler, D, et al.
Cyhoeddwyd: (2008)

The cardiotoxicity of antimalarials
Cyhoeddwyd: (2017)

A 3D hybrid-shot spiral sequence for hyperpolarized 13C imaging
gan: Tyler, D, et al.
Cyhoeddwyd: (2020)

In vivo mouse cardiac hyperpolarized magnetic resonance spectroscopy.
gan: Dodd, M, et al.
Cyhoeddwyd: (2013)

Hyperpolarized 13 C and 31 P MRS detects differences in cardiac energetics, metabolism, and function in obesity, and responses following treatment
gan: Lewis, AJM, et al.
Cyhoeddwyd: (2024)

Non-invasive in vivo assessment of cardiac metabolism in the healthy and diabetic human heart using hyperpolarized 13C MRI
gan: Rider, OJ, et al.
Cyhoeddwyd: (2020)

Rescue of myocardial energetic dysfunction in diabetes through the correction of mitochondrial hyperacetylation by honokiol
gan: Kerr, M, et al.
Cyhoeddwyd: (2020)

Hyperpolarized 13C MRI: A novel approach for probing cerebral metabolism in health and neurological disease
gan: Grist, JT, et al.
Cyhoeddwyd: (2020)

Clinical cardiovascular applications of hyperpolarized magnetic resonance
gan: Lewis, AJM, et al.
Cyhoeddwyd: (2020)

Cardiotoxicity of antimalarial drugs.
gan: White, N
Cyhoeddwyd: (2007)

Determination of cardiac metabolism in vivo with hyperpolarized carbon-13 magnetic resonance
gan: Schroeder, M, et al.
Cyhoeddwyd: (2007)

Use of Hyperpolarized Magnetic Resonance for Non-Invasive Observation of Metabolic Regulation
gan: Schroeder, M, et al.
Cyhoeddwyd: (2008)

IMPAIRED IN VIVO MITOCHONDRIAL KREBS CYCLE ACTIVITY FOLLOWING MYOCARDIAL INFARCTION ASSESSED USING HYPERPOLARIZED MAGNETIC RESONANCE SPECTROSCOPY
gan: Dodd, M, et al.
Cyhoeddwyd: (2013)

Cardiovascular Applications of Hyperpolarized MRI.
gan: Tyler, D
Cyhoeddwyd: (2011)

The development and application of new hyperpolarized magnetic resonance spectroscopy techniques for the non-invasive assessment of metabolism in the rodent heart
gan: Dodd, MS
Cyhoeddwyd: (2012)

Impaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy.
gan: Dodd, M, et al.
Cyhoeddwyd: (2014)

Myocardial substrate metabolism in obesity
gan: Rider, O, et al.
Cyhoeddwyd: (2012)

Myocardial substrate metabolism in obesity.
gan: Rider, O, et al.
Cyhoeddwyd: (2013)

Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy.
gan: Schroeder, M, et al.
Cyhoeddwyd: (2009)

In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance.
gan: Schroeder, M, et al.
Cyhoeddwyd: (2008)