Hyperpolarized 13c magnetic resonance spectroscopy identifies changes to myocardial metabolic fluxes in a rat model of doxorubicin-induced cardiotoxicity

Hyperpolarized 13c magnetic resonance spectroscopy identifies changes to myocardial metabolic fluxes in a rat model of doxorubicin-induced cardiotoxicity

Bibliografiske detaljer
Main Authors:	Timm, KN, Miller, JJ, Ball, V, Henry, JA, Savic, D, Dodd, MS, Tyler, DJ
Format:	Conference item
Sprog:	English
Udgivet:	BMJ 2018

Lignende værker

Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI.
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af: Ball, DR, et al.
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Multi-parametric MRI evaluation of doxorubicin-induced cardiotoxicity in a canine model
af: Hu, C, et al.
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Hyperpolarized magnetic resonance shows that the antiischemic drug meldonium leads to increased flux through pyruvate dehydrogenase in vivo resulting in improved postischemic function in the diabetic heart
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Proof-of-principle demonstration of direct metabolic imaging following myocardial infarction using hyperpolarized 13C CMR
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af: Savic, D
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An Engineered Bivalent Neuregulin Protects Against Doxorubicin-Induced Cardiotoxicity With Reduced Proneoplastic Potential
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Mollification of doxorubicin (DOX)-mediated cardiotoxicity using conjugated chitosan nanoparticles with supplementation of propionic acid
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Linking diabetic cardiovascular disease with non-alcoholic fatty liver disease through L-carnitine: A hyperpolarized MRS study
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Rapid, B1-insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux
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Robust and high resolution hyperpolarized metabolic imaging of the rat heart at 7 t with 3d spectral-spatial EPI.
af: Miller, J, et al.
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Susceptibility‐induced distortion correction in hyperpolarized echo planar imaging
af: Miller, JJ, et al.
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Application of hyperpolarized magnetic resonance in the study of cardiac metabolism
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The cardiotoxicity of antimalarials
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A 3D hybrid-shot spiral sequence for hyperpolarized 13C imaging
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In vivo mouse cardiac hyperpolarized magnetic resonance spectroscopy.
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Hyperpolarized 13 C and 31 P MRS detects differences in cardiac energetics, metabolism, and function in obesity, and responses following treatment
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Clinical cardiovascular applications of hyperpolarized magnetic resonance
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Cardiotoxicity of antimalarial drugs.
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Cardiovascular Applications of Hyperpolarized MRI.
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The development and application of new hyperpolarized magnetic resonance spectroscopy techniques for the non-invasive assessment of metabolism in the rodent heart
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Impaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy.
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Myocardial substrate metabolism in obesity
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Myocardial substrate metabolism in obesity.
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Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy.
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In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance.
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