A mathematical model of the phosphoinositide pathway

Phosphoinositides are signalling lipids that constitute a complex network regulating many cellular processes. We propose a computational model that accounts for all species of phosphoinositides in the plasma membrane of mammalian cells. The model replicates the steady-state of the pathway and most k...

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Bibliographic Details
Main Authors: Olivença, DV, Uliyakina, I, Fonseca, LL, Amaral, MD, Voit, EO, Pinto, FR
Format: Journal article
Language:English
Published: Nature Publishing Group 2018