Statistical methodology for the evaluation of vaccine efficacy in a phase III multi-centre trial of the RTS, S/AS01 malaria vaccine in African children.

BACKGROUND: There has been much debate about the appropriate statistical methodology for the evaluation of malaria field studies and the challenges in interpreting data arising from these trials. METHODS: The present paper describes, for a pivotal phase III efficacy of the RTS, S/AS01 malaria vacci...

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Bibliographic Details
Main Authors: Lievens, M, Aponte, J, Williamson, J, Mmbando, B, Mohamed, A, Bejon, P, Leach, A
Format: Journal article
Language:English
Published: BioMed Central 2011