Refocusing antibody responses by chemical modification of vaccine antigens
<p>The envelope glycoprotein (Env) of Human Immunodeficiency Virus 1 (HIV-1) has developed several immune-evasion mechanisms to avoid the induction of neutralising antibodies, including immunodominant non-neutralising epitopes, conformational flexibility of conserved epitopes, and spontaneous...
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Format: | Thesis |
Language: | English |
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2014
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