Refocusing antibody responses by chemical modification of vaccine antigens

<p>The envelope glycoprotein (Env) of Human Immunodeficiency Virus 1 (HIV-1) has developed several immune-evasion mechanisms to avoid the induction of neutralising antibodies, including immunodominant non-neutralising epitopes, conformational flexibility of conserved epitopes, and spontaneous...

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Bibliographic Details
Main Author: Schiffner, T
Other Authors: Sattentau, Q
Format: Thesis
Language:English
Published: 2014
Subjects: