Manual and automated Cu-mediated radiosynthesis of the PARP inhibitor [18F]olaparib

Positron emission tomography (PET) is a diagnostic nuclear imaging modality that relies on automated protocols to prepare agents labeled with a positron-emitting radionuclide (e.g., 18F). In recent years, new reactions have appeared for the 18F-labeling of agents that are difficult to access by appl...

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Bibliographic Details
Main Authors: Guibbal, F, Isenegger, PG, Wilson, TC, Pacelli, A, Mahaut, D, Sap, JBI, Taylor, NJ, Verhoog, S, Preshlock, S, Hueting, R, Cornelissen, B, Gouverneur, V
Format: Journal article
Language:English
Published: Nature Research 2020