Structural basis for IL-33 recognition and its antagonism by the helminth effector protein HpARI2
IL-33 plays a significant role in inflammation, allergy, and host defence against parasitic helminths. The model gastrointestinal nematode Heligmosomoides polygyrus bakeri secretes the Alarmin Release Inhibitor HpARI2, an effector protein that suppresses protective immune responses and asthma in its...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Nature Research
2024
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