Comprehensive identification of arginine methylation in primary T cells reveals regulatory roles in cell signalling

The impact of protein arginine methylation on the regulation of immune functions is virtually unknown. Here, we apply a novel method—isomethionine methyl-SILAC—coupled with antibody-mediated arginine-methylated peptide enrichment to identify methylated peptides in human T cells by mass spectrometry....

Full description

Bibliographic Details
Main Authors: Geoghegan, V, Guo, A, Trudgian, D, Thomason, B, Acuto, O
Format: Journal article
Language:English
Published: Nature Publishing Group 2015
Subjects: