Within-sibship GWAS of 25 phenotypes improve estimates of direct genetic effects
Estimates from genome-wide association studies of unrelated individuals (GWAS) capture effects of inherited genetic variation (direct effects), demography (population stratification, assortative mating) and genetic nurture from relatives (indirect genetic effects). GWAS using family-based designs...
Main Authors: | , , , , , , , , |
---|---|
Other Authors: | |
Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2022
|