Mathematical modelling of telomere length dynamics

Telomeres are repetitive DNA sequences located at the ends of chromosomes. During cell division, an incomplete copy of each chromosome’s DNA is made, causing telomeres to shorten on successive generations. When a threshold length is reached replication ceases and the cell becomes ‘senescent’. In thi...

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Bibliographic Details
Main Authors: Wattis, JAD, Qi, Q, Byrne, HM
Format: Journal article
Language:English
Published: Springer 2019