Molecular radiotherapy using cleavable radioimmunoconjugates that target eGFR and γH2AX
Many anticancer therapies, including ionizing radiation (IR), cause cytotoxicity through generation ofDNA double-strand breaks (DSB). Delivery of therapeutic radionuclides to DNA DSB sites can amplify this DNA damage, for additional therapeutic gain. Herein,wereport on two radiopharmaceuticals, radi...
| Main Authors: | , , , |
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| Format: | Journal article |
| Published: |
2013
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