Molecular radiotherapy using cleavable radioimmunoconjugates that target eGFR and γH2AX
Many anticancer therapies, including ionizing radiation (IR), cause cytotoxicity through generation ofDNA double-strand breaks (DSB). Delivery of therapeutic radionuclides to DNA DSB sites can amplify this DNA damage, for additional therapeutic gain. Herein,wereport on two radiopharmaceuticals, radi...
Main Authors: | , , , |
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Format: | Journal article |
Published: |
2013
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Molecular radiotherapy using cleavable radioimmunoconjugates that target EGFR and γH2AX.
Published 2013
Journal article