Exon tethering in transcription by RNA polymerase II.

There is an emerging consensus that RNA polymerase II (RNA Pol II) transcription and pre-mRNA processing are tightly coupled events. We show here that exons flanking an intron that has been engineered to be co-transcriptionally cleaved are accurately and efficiently spliced together. These data unde...

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Detalhes bibliográficos
Principais autores: Dye, M, Gromak, N, Proudfoot, N
Formato: Journal article
Idioma:English
Publicado em: 2006