In vivo human keyhole limpet haemocyanin challenge in early phase drug development: a systematic review
<p>Experimental exposure of healthy volunteers to the T-cell dependent neoantigen keyhole limpet hemocyanin (KLH) permits the evaluation of immunomodulatory investigational medicinal product (IMP) pharmacology prior to the recruitment of patient populations. Despite widespread use, no standard...
Main Authors: | Drennan, PG, Karponis, K, Richards, D, Coles, M, Fullerton, J |
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Format: | Journal article |
Language: | English |
Published: |
Wiley
2022
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