Cellular electron cryo tomography and in situ sub-volume averaging reveal the context of microtubule-based processes

Electron cryo-tomography (cryoET) is currently the only technique that allows the direct observation of proteins in their native cellular environment. Sub-volume averaging of electron tomograms offers a route to increase the signal-to-noise of repetitive biological structures, such improving the inf...

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Bibliographic Details
Main Authors: Grange, M, Grünewald, K, Vasishtan, D
Format: Journal article
Language:English
Published: Elsevier 2016