Side-chain conformational disorder in a molten globule: molecular dynamics simulations of the A-state of human alpha-lactalbumin.

Molten globules are compact, partially folded forms of proteins consisting of an ensemble of interconverting conformers with disorder in the side-chain packing across the ensemble. Using insights from experimental data a strategy has been devised to describe this side-chain disorder in a molten glob...

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Bibliographic Details
Main Authors: Smith, L, Dobson, C, van Gunsteren, W
Format: Journal article
Language:English
Published: 1999