Pan-cancer characterisation of microRNA with hallmarks of cancer reveals role of microRNA-mediated downregulation of tumour suppressor genes

microRNAs are key regulators of the human transcriptome across a number of diverse biological processes, such as development, aging and cancer, where particular miRNAs have been identified as tumour suppressive and oncogenic. In this work, we elucidate, in a comprehensive manner, across 15 epithelia...

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Detalles Bibliográficos
Autores principales: Dhawan, A, Scott, J, Harris, A, Buffa, F
Formato: Journal article
Publicado: Nature Research 2018