Lipid binding attenuates channel closure of the outer membrane protein OmpF

Strong interactions between lipids and proteins occur primarily through association of charged headgroups and amino acid side chains, rendering the protonation status of both partners important. Here we use native mass spectrometry to explore lipid binding as a function of charge of the outer membra...

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Bibliographic Details
Main Authors: Liko, I, Degiacomi, M, Lee, S, Newport, T, Gault, J, Reading, E, Hopper, J, Housden, N, White, P, Colledge, M, Sula, A, Wallace, B, Kleanthous, C, Stansfeld, P, Bayley, H, Benesch, J, Allison, T, Robinson, C
Format: Journal article
Language:English
Published: National Academy of Sciences 2018