Unified single-cell analysis of testis gene regulation and pathology in 5 mouse strains.

To fully exploit the potential of single-cell functional genomics in the study of development and disease, robust methods are needed to simplify the analysis of data across samples, time-points and individuals. Here we introduce a model-based factor analysis method, SDA, to analyse a novel 57,600-ce...

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Bibliographic Details
Main Authors: Jung, M, Wells, D, Rusch, J, Ahmad, S, Marchini, J, Myers, SR, Conrad, DF
Format: Journal article
Language:English
Published: eLife Sciences Publications 2019