Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: a systematic review and meta-analysis

BACKGROUND: Guidelines recommend intensive blood pressure (BP) lowering in patients at high risk. While placebo-controlled trials have demonstrated 22% reductions in coronary heart disease (CHD) and stroke associated with a 10-mmHg difference in systolic BP, it is unclear if more intensive BP loweri...

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Bibliographic Details
Main Authors: Lv, J, Neal, B, Ehteshami, P, Ninomiya, T, Woodward, M, Rodgers, A, Wang, H, MacMahon, S, Turnbull, F, Hillis, G, Chalmers, J, Perkovic, V
Format: Journal article
Published: Public Library of Science 2012