Negative epistasis between α+ thalassaemia and sickle cell trait can explain interpopulation variation in South Asia.
Recent studies in Kenya and Ghana have shown that individuals who inherit two malaria-protective genetic disorders of haemoglobin-α(+) thalassaemia and sickle cell trait-experience a much lower level of malaria protection than those who inherit sickle cell trait alone. We have previously demonstrate...
Váldodahkkit: | , , , |
---|---|
Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
2011
|