Negative epistasis between α+ thalassaemia and sickle cell trait can explain interpopulation variation in South Asia.

Negative epistasis between α+ thalassaemia and sickle cell trait can explain interpopulation variation in South Asia.

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Recent studies in Kenya and Ghana have shown that individuals who inherit two malaria-protective genetic disorders of haemoglobin-α(+) thalassaemia and sickle cell trait-experience a much lower level of malaria protection than those who inherit sickle cell trait alone. We have previously demonstrate...

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Detalles Bibliográficos
Main Authors: Penman, B, Habib, S, Kanchan, K, Gupta, S
Formato: Journal article
Idioma:English
Publicado: 2011
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