Induction of cognitive impairment by scopolamine and noncholinergic agents in rhesus monkeys.
In primates, treatment with scopolamine impairs performance of a spatial delayed response task in a way which mimics deficits seen spontaneously in aged primates and demented patients. Despite their efficacy in reversing scopolamine induced disruption, the effects of cholinergic agonists on cognitio...
Main Authors: | , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1991
|