Induction of cognitive impairment by scopolamine and noncholinergic agents in rhesus monkeys.
In primates, treatment with scopolamine impairs performance of a spatial delayed response task in a way which mimics deficits seen spontaneously in aged primates and demented patients. Despite their efficacy in reversing scopolamine induced disruption, the effects of cholinergic agonists on cognitio...
Main Authors: | Rupniak, N, Samson, N, Steventon, M, Iversen, S |
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Format: | Journal article |
Language: | English |
Published: |
1991
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