Asymmetric synthesis of N,O,O,O-tetra-acetyl D-lyxo-phytosphingosine, jaspine B (pachastrissamine) and its C(2)-epimer

The highly diastereoselective conjugate addition of lithium (S)-N-benzyl-N-(α-methylbenzyl)amide to a γ-silyloxy-α,β-unsaturated ester and in situ enolate oxidation with (+)-(camphorsulfonyl)oxaziridine has been used as the key step in the asymmetric synthesis of N,O,O,O-tetra-acetyl d-lyxo-phytosph...

Полное описание

Библиографические подробности
Главные авторы: Abraham, E, Candela-Lena, J, Davies, S, Georgiou, M, Nicholson, R, Roberts, P, Russell, A, Sanchez-Fernandez, E, Smith, A, Thomson, J
Формат: Journal article
Язык:English
Опубликовано: 2007