5α-reductase type 2 regulates glucocorticoid action and metabolic phenotype in human hepatocytes

Glucocorticoids and androgens have both been implicated in the pathogenesis of nonalcoholic fatty liver disease (NAFLD); androgen deficiency in males, androgen excess in females, and glucocorticoid excess in both sexes are associated with NAFLD. Glucocorticoid and androgen action are regulated at a...

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Bibliographic Details
Main Authors: Nasiri, M, Nikolaou, N, Parajes, S, Krone, N, Valsamakis, G, Mastorakos, G, Hughes, B, Taylor, A, Bujalska, I, Gathercole, L, Tomlinson, J
Format: Journal article
Language:English
Published: Endocrine Society 2015