Association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania.

The indigenous populations of the South Pacific experience a high burden of rheumatic heart disease (RHD). Here we report a genome-wide association study (GWAS) of RHD susceptibility in 2,852 individuals recruited in eight Oceanian countries. Stratifying by ancestry, we analysed genotyped and impute...

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Bibliographic Details
Main Authors: Parks, T, Mirabel, M, Kado, J, Auckland, K, Nowak, J, Rautanen, A, Mentzer, A, Marijon, E, Jouven, X, Perman, M, Cua, T, Kauwe, J, Allen, J, Taylor, H, Robson, K, Deane, C, Steer, A, Hill, A, Pacific Islands Rheumatic Heart Disease Genetics Network
Format: Journal article
Language:English
Published: Nature Publishing Group 2017