Germline sequencing DNA repair genes in 5,545 men with aggressive and non-aggressive prostate cancer

<p><strong>BACKGROUND:</strong> There is an urgent need to identify factors specifically associated with aggressive prostate cancer (PCa) risk. We investigated whether rare pathogenic, likely pathogenic, or deleterious (P/LP/D) germline variants in DNA repair genes are associated w...

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Bibliographic Details
Main Authors: Darst, BF, Dadaev, T, Saunders, E, Sheng, X, Wan, P, Pooler, L, Xia, LY, Chanock, S, Berndt, SI, Gapstur, SM, Stevens, V, Albanes, D, Weinstein, SJ, Gnanapragasam, V, Giles, GG, Nguyen-Dumont, T, Milne, RL, Pomerantz, M, Schmidt, JA, Mucci, L, Catalona, WJ, Hetrick, KN, Doheny, KF, MacInnis, RJ, Southey, MC, Eeles, RA, Wiklund, F, Kote-Jarai, Z, Conti, DV, Haiman, CA
Format: Journal article
Language:English
Published: Oxford University Press 2020