ARCII: A Phase II trial of the HIV protease inhibitor Nelfinavir in combination with chemoradiation for locally advanced inoperable pancreatic cancer

Background and purpose Nelfinavir can enhance intrinsic radiosensitivity, reduce hypoxia and improve vascularity. We conducted a phase II trial combining nelfinavir with chemoradiotherapy (CRT) for locally advanced inoperable pancreatic cancer (LAPC). Materials and methods Radiotherapy (50.4 Gy/28...

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Príomhchruthaitheoirí: Wilson, J, Fokas, E, Dutton, S, Hawkins, M, al., E
Formáid: Journal article
Foilsithe / Cruthaithe: Elsevier 2016