Microevolution of Burkholderia pseudomallei during an acute infection.
We used whole-genome sequencing to evaluate 69 independent colonies of Burkholderia pseudomallei isolated from seven body sites of a patient with acute disseminated melioidosis. Fourteen closely related genotypes were found, providing evidence for the rapid in vivo diversification of B. pseudomallei...
Main Authors: | Limmathurotsakul, D, Holden, M, Coupland, P, Price, E, Chantratita, N, Wuthiekanun, V, Amornchai, P, Parkhill, J, Peacock, S |
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格式: | Journal article |
语言: | English |
出版: |
American Society for Microbiology
2014
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