Therapeutic targeting of PRMT5 and mutant ACVR1 in paediatric glioma

Diffuse Intrinsic Pontine Glioma (DIPG) is a universally fatal paediatric brainstem tumour with a median overall survival of 9-11 months. The unique genetic, anatomical and developmental identity of the tumour means that there are currently no effective chemotherapies or targeted therapies. This the...

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Bibliographic Details
Main Author: Brown, EJ
Other Authors: Bullock, A
Format: Thesis
Language:English
Published: 2021
Subjects: